Knowledge, Principles, and Clinical Consequences of Drug Interaction: A Cross-Sectional Study in Subratha Teaching Hospital, Libya

Kawther M. Ibrahem; Wafa A. Said; Ebtesam Beshna; Fayza R. ALneser; Mohamed M. Rhagem; Wafa M. Ibrahem; Najia A. Mahdawi

doi:10.55940/medphar202482

Authors

Kawther M. Ibrahem Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Zawia, Libya
Wafa A. Said Department of Anesthesia and Intensive Care, Faculty of Medical Technology, University of Alzaytuna, Libya
Ebtesam A. Beshna Department of Pharmaceutics and Pharmaceutical Industry, Faculty of Pharmacy, University of Zawia, Libya
Fayza R. ALneser Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Zawia, Libya
Mohamed M. Rhagem Department of Zoology, Faculty of Science, University of Zawia, Libya
Wafa M. Ibrahem Departement of Parasitology, Faculty of Medicine, University of Zawia, Libya
Najia Al. Mahdawi Department of Medicine. Faculty of Medicine University of Gharyan Libya

DOI:

https://doi.org/10.55940/medphar202482

Keywords:

Aspirin, Cross-Sectional Studies, Drug- interaction, Prevalence

Abstract

Background: Drug interactions are considered one of the adverse drug events, which are known as drug interaction injuries (DDIS), which can lead to severe side effects in addition to their impact on therapeutic effectiveness.

Objective: The study aimed to identify the concept of drug interactions, how they occur, and their types, evaluate the prevalence among patients, and determine the medications most susceptible to drug interactions. It also aimed to determine the levels of potential drug interactions from prescriptions collected randomly from the Internal Medicine Department at Sabratha Teaching Hospital

Methods: A cross-sectional study was conducted at Sabratha Teaching Hospital, Libya. Prescriptions were randomly collected from the Internal Medicine Department, and potential drug interactions were analyzed. The study evaluated the prevalence and types of drug interactions, focusing on identifying the most susceptible medications and the age groups most affected.

Results: The study found that there was a high percentage of drug interactions among patients who were admitted as shelter cases, and the age group most exposed to drug interactions was between 61 and 80 years, at a rate of 31.5%.

Conclusion: Among the medications that had the most drug interactions with a large number of medications was aspirin.

Author Biographies

Wafa M. Ibrahem, Departement of Parasitology, Faculty of Medicine, University of Zawia, Libya

Najia Al. Mahdawi, Department of Medicine. Faculty of Medicine University of Gharyan Libya

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